Establishing Your Dosage
We always recommend you “start low, and go slow” as you establish your dose.
CBD is biphasic, meaning it can be energizing or sedating, depending on the amount consumed. In smaller doses, CBD can be energizing and mood enhancing. In larger doses, it can induce drowsiness. What is considered a small or large dose varies depending on how your body responds to cannabinoids, and your issues with pain, inflammation, or anxiety.
|Sublingual Drops/Tinctures||500mg/10mL = 2mg per drop|
1000mg/10mL = 4mg per drop
|Shake well before use. Place and hold 10-12mg under the tongue for 60sec before swallowing. Take suggested dose 1x per day for three days. If you do not feel the desired effects following three days, increase your dose to 20mg for three more days. Continue to adjust drops every three days till desired effect is achieved. Once you have established a systemic dose in your body, you may decrease mgs per day to a maintenance dose.|
|Topicals (mild to severe)||50mg/1oz (mild-to-moderate pain)|
100mg/1oz (healing balm)
300mg/1oz (severe pain)
|Apply generously to affected area, and massage balm till thoroughly absorbed. Apply consistently (2-3x per day) till pain and inflammation cease. Repeat as needed. Intended for localized application, and external use only. *Note: Our wintergreen scent, Sport - Cooling, and Sport - Warming are not intended for persons under the age of 12.|
|Tablets||30mg of CBD per tablet, 30 tablets per bottle||For managing consistent pain, inflammation, and/or stress, take 1 tablet every
evening (Calm tablets) or every morning/afternoon (Focus, Recovery, Power tablets) for 3-5 days. If issues persist, increase dosage to 2 tablets for 3-5 days. For temporary relief from aches and pains, take 1-2 tablets before bed (Calm tablets) or in the morning/afternoon (Focus, Recovery, Power tablets), as needed. CBD interacts with each body differently, so start low, and go slow!
|Migraine Treatment||100mg/10mL||Shake well before use. Apply small amount of roll-on at both temples, behind the ears, and at the base of neck. Allow to absorb, and wait 30min. If after 30min, you have not experienced any results, reapply and wait an additional 30min. Note: Do not apply to open wounds. Keep away from both eyes and mouth. Not intended for children under the age of 12yrs old. Do not use if you have a known allergy to any ingredients.|
|Chewing Gum||10mg of CBD per piece, 4 pieces per pack||Chew one piece of our chewing gum slowly, until you begin salivating. Place the gum between your cheek and gums for 60sec to allow for maximum absorption. After about a minute, begin chewing again. Continue to repeat this process till flavor is gone (about 30min). Repeat as needed.|
|Oral Drops for Dogs||500mg/10mL = 2mg per drop|
1 drop (2mg) per 10lbs of dog's weight
|Shake well before use. Drop suggested dose onto your dog's favorite treat or snack. To ensure maximum absorption, make sure dose is consumed in one bite. For anxiety: Wait an hour after ingestion. If your dog is still experiencing anxiety following the suggested dose, give them another single drop on their favorite treat or snack, and wait another hour. Continue to provide an additional drop every hour till desired effect is achieved. For Inflammation and Pain: Continue with suggested dose for three days. If your dog does not respond to the suggested dose, increase dose by one drop (2mg) for three more days. Continue to adjust dose every three days till desired effect is achieved. Once you have established a systemic dose, you may decrease mgs per day to a maintenance dose.|
|Dog Treats - Calm and Composed||5mg per treat, 20 treats per bag||Dogs less than 30lbs can start with 1 treat as needed. Dogs more than 30lbs can start with 2 treats as needed. If after an hour, your dog has not responded to the recommendations above, feed them another 1/2 of a treat, and wait another hour. Once you've established your dog's calming dose (1 treat, 1.5 treats, etc.), then moving forward, that is how much your dog requires. Large breeds (100+lbs) can consume up to three treats per day.|
|Dog Treats - Joint Health||5mg per treat, 20 treats per bag||Dogs less than 30lbs can start with 1/2 treat as needed. Dogs more than 30lbs can start with 1 treat as needed. If after three days, your dog has not responded to the recommendations above, increase their dose by 1/2 of a treat for another three days. Continue to adjust dose by 1/2 treat till the desired effect is achieved. Once you've established your dog's calming dose (1 treat, 1.5 treats, etc.), then moving forward, that is how much your dog requires. Once you have established a systemic dose, you may decrease mgs per day to a maintenance dose. Large breeds (100+lbs) can consume up to three treats per day.|
|Oral Drops for Cats||250mg/10mL = 1mg per drop|
1 drop (1mg) per 5lbs of your cat's weight
|Shake well before use. Drop suggested dose onto your cat's favorite treat or snack. To ensure maximum absorption, make sure dose is consumed in one bite. For anxiety: Wait an hour after ingestion. If your cat is still experiencing anxiety following the suggested dose, give them another single drop on their favorite treat or snack, and wait another hour. Continue to provide an additional drop every hour till desired effect is achieved. For Inflammation and Pain: Continue with suggested dose for three days. If your cat does not respond to the suggested dose, increase dose by one drop (1mg) for three more days. Continue to adjust dose every three days till desired effect is achieved. Once you have established a systemic dose, you may decrease mgs per day to a maintenance dose.|
Establishing a recommended dose of cannabidiol (CBD) for relief from a particular ailment is difficult for a variety reasons. Firstly, the bioavailability (the proportion of a substance that enters the circulation when introduced into the body, so as to have an active effect) of CBD varies, depending upon how it is administered. Meaning, if you were applying CBD topically verses taking it orally, the amount of CBD to enter your bloodstream would vary significantly. Listed below are the different means of administering CBD in order of highest to lowest bioavailability:
- Inhalation (vaporizer): Highest bioavailability, used to ease systemic pain, inflammation, anxiety, and stress. When inhaled, the cannabinoids and terpenes pass directly into the bloodstream from the lungs. Peak blood levels are achieved almost immediately, but do drop-off faster than other applications. We recommend inhalation for immediate relief, combined with etiher a sublingual or oral application to maintain relief. For details regarding our preloaded vaporizer kit, contact [email protected]
- Sublingual (drops/tinctures): Used to ease systemic pain, inflammation, anxiety, and stress. The cannabinoids and terpenes diffuse into the blood through various capillaries found in the connective tissue under the tongue. Absorption rate varies, dependent on how the cannabinoids are metabolized by your body. Our sublingual drops include a minimum of 50mg/mL, available in our energizing Sativa or sedating Indica blend of terpenes. We also have sublinguals available for those suffering from Menstrual and Menopausal symptoms.
- Oral (gum, tablets, fruit chews): Used to ease systemic pain, inflammation, anxiety, and stress. Slower means of consuming cannabinoids and terpenes because the active ingredients must first pass through the gastrointestinal tract during digestion before entering the bloodstream, which generally takes 30-90min. The potency of the cannabinoids and terpenes are further minimized due to “first-pass metabolism” (the phenomenon whereby the concentration of a drug is greatly reduced before it reaches the systemic circulation) in the digestive tract. At Rx Remedies, we include proprietary plant extracts to our orally-consumed products to increase the bioavailability by up to 50%!
- Topical (balms/roll-ons/lotion): Used to treat localized pain and inflammation, delivering active ingredients to the bloodstream through the skin. Effects generally take 5-15min, and can last up to 12hrs. Our topicals include an additional plant-based remedies for both pain and inflammation, as well as known skin penetrants, allowing for greater absorption of our active ingredients.
The basis of comparison for all other means of administration is intravenously, which is assumed to have 100% bioavailability. We are not suggesting intravenous administration of our CBD products, but rather clarifying that when studies reveal the bioavailability of CBD, it is by comparison to an intravenous application.
Secondly, how our bodies respond to cannabinoids effects how many milligrams one should consume, and how our bodies respond is based solely upon our endocannabinoid system. The endocannabinoid system (ECS) is responsible for a variety of biological functions, and can be found in each and every mammalian body. It naturally synthesizes the endocannabinoids our bodies produce, and can also be activated by phytocannabinoids, such as CBD and THC, as well as by terpenes, the pungent oils secreted by the cannabis plant. CBD and terpenes work synergistically together, meaning the therapeutic benefits of each are greatly intensified when combined. Your sensitivity (or lack-thereof) to CBD is based upon your body’s individual ECS, and its response to cannabinoids and terpenes. This is why one’s response to cannabis can be so stark from one person to the next.
As an example, if three different people were to consume a strain of cannabis high in THC, you could potentially have three completely different reactions. One person could feel relaxed and at ease, one could feel anxious or paranoid, and the other could feel elated and energetic. Similarly, if three different people were to consume five drops of our sublingual drops (10mg of CBD), one could feel tired, one could feel energized, and the other could feel nothing at all. The first person may need to take less, as 10mg is too sedating. The second is probably taking the perfect dose, and the third requires a bit more.
Titration is a technique where a solution of a known concentration is used to determine the concentration of an unknown solution, or the the process of slowly increasing one medicine or liquid with another medicine or liquid. In regards of dosing CBD, it deals with taking small amounts of CBD until you’ve reached your own personal “magic number”.
For more information on CBD and doses, check out PubMed.gov, and ProjectCBD.org. If you have additional questions about our CBD products or need help selecting a product, contact us at [email protected]. We’re here to help!